Job Title

Senior Biopharmaceutical StatisticianAbout Us:Eupraxia is a clinical-stage biotechnology company focused on developing locally delivered, extended-release products that have the potential to address therapeutic areas with high unmet medical need. DiffuSphere, a proprietary, polymer-based micro-sphere technology, is designed to facilitate targeted drug delivery of both existing and novel drugs. The technology is designed to support an extended duration of effect and delivery of drugs in a hyper-localized fashion, targeting only the tissues that physicians want to treat. We believe the potential for fewer adverse events may be achieved through the precision targeting and the stable and flat delivery of the active ingredient when using the DiffuSphere technology, versus the peaks and troughs seen with more traditional drug delivery methods. The precision of Eupraxia's DiffuSphere technology platform has the potential to augment and transform existing FDA-approved drugs to improve their safety, tolerability, efficacy and duration of effect. The potential uses in therapeutic areas may go beyond pain and inflammatory gastrointestinal disease, where Eupraxia currently is developing advanced treatments, also to be applicable in oncology, infectious disease and other critical disease areas.Eupraxia's EP-104GI is currently in a Phase 1b/2a trial, the RESOLVE trial, for the treatment of EoE. EP-104GI is administered as an injection into the esophageal wall, providing local delivery of drug. This is a unique treatment approach for EoE. Eupraxia also recently completed a Phase 2b clinical trial (SPRINGBOARD) of EP-104IAR for the treatment of pain due to knee osteoarthritis. The trial met its primary endpoint and three of the four secondary endpoints. In addition, Eupraxia is developing a pipeline of later and earlier-stage long-acting formulations. Potential pipeline indications include candidates for other inflammatory joint indications and oncology, each designed to improve on the activity and tolerability of currently approved drugs. For further details about Eupraxia, please visit the Company's website at: www.eupraxiapharma.com.We are looking for someone who would like to work for a fast-paced, growing company that fosters a creative spirit and integrated teamwork and is eligible to work in North America.Job Description:We are seeking a sharp, flexible, and innovative Senior Biostatistician to lead the statistical strategy for our clinical development programs and oversee data management. This is a hands-on, high-impact role ideal for someone who thrives in a fast-paced biotech environment and enjoys shaping programs from early development through submission.The successful candidate will bring advanced modeling and statistical expertise, creative problem-solving skills, and strong leadership abilities. You will play a central role in clinical trial design, data interpretation, regulatory submissions, and data-driven decision-making.Reports to: Chief Medical OfficerKey Responsibilities:Statistical LeadershipServe as the lead statistician across multiple clinical trials (Phase 13).Design and drive statistical strategy for clinical development plans and regulatory submissions.Develop protocols, statistical analysis plans (SAPs), and randomization strategies.Contribute to and defend key statistical components in regulatory filings (IND, NDA, BLA).Oversee statistical programming, analysis, and validation (in-house or outsourced).Deliver high-quality study reports and exploratory analyses that unlock value beyond primary endpoints.Modeling & SimulationBuild and apply advanced statistical and PK/PD models to support dose selection, trial optimization, and forecasting.Run pre-study scenarios using Bayesian and frequentist approaches.Integrate real-time data to guide ongoing clinical decision-making.Data Visualization & CommunicationCreate impactful, theory-informed visualizations.Leverage interactive graphics to surface insights for internal and external stakeholders.Effectively translate complex findings into clear narratives for diverse audiences.Data Management OversightProvide strategic and operational oversight of the data management function.Ensure data integrity, consistency, and audit readiness across studies.Collaborate closely with internal and CRO data teams to build scalable systems and processes.Cross-functional CollaborationWork closely with Clinical Operations, Medical/Pharmacovigilance, Regulatory Affairs, Medical Writing, and external partners.Support executive decision-making with statistical insight and data-driven recommendations.Mentor junior staff and contribute to a culture of scientific rigor and continuous improvement.Qualifications:Required:Ph.D. or M.Sc. in Biostatistics, Statistics, or a related field.58+ years of industry experience in clinical trial biostatistics.Deep understanding of clinical trial design, ICH/GCP guidelines, and regulatory standards.Hands-on experience with SAS and R; familiarity with modern data science tools a plus.Experience with regulatory interactions / presentations and submission support.Proven ability to drive statistical strategy and influence key stakeholders.Preferred: Experience in oncology, rare disease, rheumatology, gastroenterology, or inflammation and immunology space.Prior experience with supporting later stage regulatory filings including NDA or MAA Familiarity with adaptive designs, Bayesian methods, and model-informed drug development.Prior exposure to omics analysis, data mining, or real-world data integration.Strong presentation skills and a demonstrated ability to communicate with executives and regulators.Additional attributes:Intellectually curious, adaptable, and creative.Both strategic and hands-onyou love the details but can see the big picture.Strong sense of ownership and accountability.Clear communicator, collaborative team player, and natural problem solver.Passionate about innovation in biostatistics and making an impact on patient care.Salary Range:CAD$ 190,000 230,000 annuallyWithin the posted range, individual pay is determined by job-related skills, relevant experience, education and/or training. Please note that the range details above reflect the base pay only. A bonus will be available based upon performance and remaining in post for the agreed contract duration. We also have a competitive benefits package on offer. This is an opportunity to work in a small, entrepreneurial, and highly motivating environment, with a strong emphasis on work/life balance and a supportive company culture. How to Apply:Please send your CV and cover letter to careers@eupraxiapharma.com. While only short-listed candidates will be notified, we thank each applicant for their submission.