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Staff - Non Union Job Category Non Union Technicians and Research Assistants Job Profile Non Union Salaried - Research Assistant /Technician 3 Job Title Zandstra lab - Non Union Salaried - Research Assistant /Technician 3 Department Zandstra Laboratory | School of Biomedical Engineering | Faculty of Medicine Compensation Range $4,567.04 - $5,385.67 CAD Monthly Posting End Date March 22, 2026. Note: Applications will be accepted until 11:59 PM on the Posting End Date. Job End Date March 1, 2027. At UBC, we believe that attracting and sustaining a diverse workforce is key to the successful pursuit of excellence in research, innovation, and learning for all faculty, staff and students. Our commitment to employment equity helps achieve inclusion and fairness, brings rich diversity to UBC as a workplace, and creates the necessary conditions for a rewarding career. Job Summary The School of Biomedical Engineering (SBME) at the University of British Columbia (UBC) is a partnership between the Faculties of Applied Science and Medicine, established in 2017. The School is a nucleus for education and training, research, and innovation in biomedical engineering, creating new knowledge, new academic and training programs, and fostering translation and innovation. Its vision is to transform health and healthcare for all, achieved through innovative research and education at the convergence of engineering, medicine and biology. Through collaborative, innovative, and interdisciplinary approaches and building on UBCs academic and research excellence, the School of Biomedical Engineering aspires to be a global leader in biomedical engineering research, education and translation. The SBME has two locations on Vancouvers campus, the Gordon B Shrum building and the Biomedical Research Centre (BRC). For more information about the School of Biomedical Engineering, please visit Status The Research Assistant/Technician will report to Principal Investigator in the Zandstra Lab and work collaboratively with other staff, students and postdoctoral fellows. Work Performed The technician will work in laboratory and animal facility setting and may be required to work occasional weekend or evening work for time-sensitive experiments. The work involves exposure to animal allergens and biological materials, including immunodeficient mice and human cells. An initial orientation will be provided on biosafety, radiation safety, and animal handling. Animal Husbandry & Colony Management Maintain and manage genetically engineered mouse colonies. Monitor animal health and welfare, identify signs of distress, and coordinate veterinary care. Maintain accurate breeding and experimental records using colony management software. Coordinate routine genotyping. Technical Procedures Perform humanized mouse model generation, including engraftment of human CD34+HSCs or immune cell products. Sublethal irradiation. Perform blood collection via tail vein and cardiac puncture techniques. Conduct live bone marrow aspirations (training will be provided). Tissue harvests (e.g. bone marrow, spleen, thymus, lymph nodes). Administer compounds via oral gavage, intraperitoneal, intravenous, and subcutaneous routes. Mice ultrasound. Flow cytometry sample preparation, acquisition and analysis (training will be provided). Monitor postprocedure recovery and elevate any concerns to senior researchers. Animal/Human primary cell genotyping, extracting DNA, and running qPCR or ddPCR on the samples. Research Support Assist in preclinical validation studies for cell therapy products. Coordinate with bioengineers on experimental design for in vivo efficacy and safety studies. Prepare singlecell suspensions from hematopoietic tissues. Process samples for downstream analysis (flow cytometry, histology, molecular biology). Maintain detailed experimental logs and contribute to data organization. Collaborate with research staff to execute experimental protocols. Compliance & Safety Ensure compliance with institutional animal care guidelines provided by the UBC Animal Care Committee (ACC). Maintain sterile technique for immunocompromised mouse handling. Follow biosafety and chemical safety protocols. Participate in required training and continuing education. Adopt the best practices for animal welfare. Coordinate tasks with the ARC Animal Facility or UBC animal facilities. Consequence of Error/Judgement This position requires a high degree of accuracy and sound judgment. Errors in animal handling, irradiation procedures, surgical techniques, or sample processing could result in animal welfare concerns, loss of valuable research specimens, compromised experimental data, and significant delays to preclinical studies. Errors in recordkeeping, genotyping, or biosafety compliance could impact research integrity and regulatory compliance. Failure to adhere to animal care and biosafety protocols may result in institutional noncompliance and suspension of research activities. Supervision Received The candidate works under general supervision of the Principal Investigator. Routine responsibilities and established protocols are performed independently. Detailed instructions and guidance are provided for new procedures or complex experimental designs. The role requires independent judgment in prioritizing tasks, troubleshooting technical issues, and ensuring compliance with institutional policies. Supervision Given None. Minimum Qualifications Completion of a relevant technical program or a university degree in a relevant discipline and a minimum three years of related experience or an equivalent combination of education and experience. Willingness to respect diverse perspectives, including perspectives in conflict with ones own. Demonstrates a commitment to enhancing ones own awareness, knowledge, and skills related to equity, diversity, and inclusion. Preferred Qualifications Bachelors degree in Biology, Animal Science, or related field, OR equivalent experience an asset. Experience working with laboratory mice. Proficiency in basic mouse handling, injections, and blood collection techniques. Knowledge of mouse genetics and breeding strategies. Basic understanding of stem cell biology and/or immunology. Strong organizational skills and attention to detail. Ability to work independently and as part of a team. Excellent attention to detail and ability to follow SOPs precisely. Problemsolving and troubleshooting experimental procedures. Completion of nimal Care training complying with the Canadian Council on Animal Care guidelines preferred. Experience generating or maintaining humanized mouse models. Experience with hematopoietic tissue processing and multiparameter flow cytometry. Experience with immunocompromised mouse strains (NSG, NRG, or similar). Knowledge of hematopoiesis and blood cell biology. Experience with colony management software (e.g., PyRat, Mosaic). Protocol writing for bioethics approval. Proficiency in mouse surgery procedures (e.g. Subcapsular kidney transplantation). Ability to lift up to 25 pounds. Comfortable working with animals and animal allergens. Ability to stand for extended periods. Manual dexterity for fine technical procedures. #J-18808-Ljbffr