Job Title

Position OverviewSynakis is seeking a highly creative and driven Postdoctoral Fellow to lead the development of long-acting drug delivery formulations, with an initial focus on glaucoma therapeutics.This role is ideal for a scientist passionate about translating cutting-edge biomaterials into clinically impactful therapies. The successful candidate will play a key role in advancing Synakis hydrogel platform toward next-generation ophthalmic treatments.Key ResponsibilitiesDesign and develop long-acting intraocular formulations using Synakis proprietary hydrogel platformOptimize drug loading, release kinetics, and stability for small molecules, prodrugs, and biologicsEngineer formulations tailored for glaucoma treatment, including sustained intraocular pressure controlEvaluate biocompatibility, degradation profiles, and ocular tolerabilityCollaborate cross-functionally with biomaterials scientists, pharmacologists, and clinical advisorsDesign and execute in vitro and in vivo studies to validate performanceContribute to intellectual property development, publications, and regulatory strategyRequired QualificationsPh.D. in Pharmaceutical Sciences, Chemical Engineering, Biomedical Engineering, or related fieldDemonstrated experience in organic synthesis and analytical chemistryDemonstrated experience in materials science and colloid formulation and characterizationDeep understanding of controlled release systems and biomaterialsProven ability to work creatively and independently in early-stage R&D environmentsPreferred QualificationsExperience with ophthalmic drug delivery or sustained delivery drug formulationsExperience with hydrogels, polymeric systems, or injectable biomaterialsKnowledge of ocular anatomy, physiology and animal models of ocular diseaseExperience working with biologics, peptides, and prodrugsFamiliarity with animal models of ocular diseaseFamiliarity with toxicology and pharmacokinetic analysisWhat Were Looking ForA highly creative problem-solver who thrives in ambiguityA scientist eager to translate fundamental science into real therapiesStrong communicator and collaborator with a startup mindsetWhy Join SynakisWork on breakthrough technology with the potential to transform vision careBe part of an early-stage, high-impact biotech shaping the future of ocular therapeuticsOpportunity to contribute directly to clinical translation and patient outcomesBe part of the prestigious lab of Prof. Molly Shoichet at the University of TorontoHow to Apply: Please send your CV and a brief statement of research interests to Thierry Nivaggioli, Ph.D. Synakis CEO at