Job Title

Zymeworks is a global biotechnology company managing a portfolio of licensed healthcare assets and developing a diverse pipeline of novel, multifunctional biotherapeutics to improve the standard of care for difficult-to-treat diseases, including cancer, inflammation, and autoimmune disease. The Companys asset and royalty aggregation strategy focuses on optimizing positive future cash flows from an emerging portfolio of licensed products such as Ziihera (zanidatamab-hrii) and other licensed products and product candidates such as pasritamig. In addition, Zymeworks is also building a portfolio of healthcare assets that can generate strong cash flows, while supporting the early-stage development of innovative medicines. We are a global company headquartered in Vancouver BC, with operations in Bellevue WA, Dublin IRE, and Singapore. Why Work With Us Nothing is more critical to our success than the quality of our team. The work we do is meaningful and impactful we care about each other as well as the patients we serve. We offer challenging career opportunities, competitive benefits and an environment that recognizes and rewards performance. This role will be located in either Vancouver, BC or Bellevue, WA or New York or Singapore or Cambridge, UK and is hybrid with a minimum of 3 days per week onsite. What Youll Do With appropriate supervision, manages the design and implementation of study protocols for a clinical development program, based on strong medical and scientific principles, knowledge of compliance and regulatory requirements, and emerging issues. Oversees projectrelated education of investigators, study site personnel, and study staff. Has responsibility for oversight of clinical studies, monitoring overall study integrity, and review, interpretation, and communication of accumulating data pertaining to safety and efficacy of the asset. Contributes to design, analysis, interpretation, and reporting of scientific content of protocols, Investigator Brochures, Clinical Study Reports, regulatory submissions and responses, and other program documents. Stays abreast of professional information and technology through conferences, medical literature, and other available training, to augment expertise in the therapeutic area. Support database design and contribute to case report form (CRF) completion guidelines. Educate internal study team members, clinical sites on protocol requirements. Collaborate with the Clinical Trial Manager (CTM) to support study startup, conduct, and closeout activities. Provide scientific input into vendor scope of work (SOW), contracts, and study charters. Partner with vendors to ensure delivery of highquality data and scientific integrity of services. Perform ongoing clinical data review, including protocol deviations, to ensure data quality, accuracy, and scientific validity. Identify data trends, summarize findings, and elevate clinical or medical concerns to the Medical Monitor as appropriate. Review MedDRA and WHODRUG coding to ensure consistency and accuracy. Represent Clinical Development on crossfunctional study teams and at internal or external meetings. May be asked to contribute to regulatory responses and discussions. Contribute to continuous improvement of clinical processes and study execution. Perform other duties as assigned. What Youll Bring Advanced degree in life sciences or a clinical field (e.g., RN, NP/ARNP, PharmD, Physician Assistant, PhD, MD, or equivalent) required. Minimum of 2+ years of relevant experience in the biopharmaceutical industry or a comparable clinical research setting preferred. Oncology experience strongly preferred. Strong ability to interpret and analyze clinical data with a focus on scientific rigor. Solid understanding of clinical development processes, GCP, and regulatory requirements. Proficiency in medical terminology. Demonstrated ability to assimilate complex scientific information quickly. Excellent analytical, problemsolving, and critical thinking skills. Strong written and verbal communication skills, with the ability to clearly convey scientific information. Highly collaborative with the ability to work effectively in crossfunctional teams. Strong organizational skills, attention to detail, and commitment to data accuracy. Ability to manage multiple priorities in a fastpaced environment and adapt to changing needs. Proficiency with Microsoft Office Suite. Total Rewards We offer a comprehensive total rewards package, which includes competitive salaries, generous benefits, an outstanding work environment, and excellent opportunities for professional growth. We regularly benchmark our compensation against leading biotechnology companies in our geographies. The base salary range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position for the location for which the job is posted and does not include bonus, equity or benefits. Within the range, individual pay is determined by a variety of factors and the salary offered may vary depending on the successful candidates location and qualifications (including, but not limited to, jobrelated knowledge, education, training, skills, and experience). Our Total Rewards Package That Includes: Industry leading vacation and paid time off Exceptional medical, dental and vision benefits by country Zymelife health and wellness benefits Employee Share Purchase Program Employee Equity Program Paid time off to volunteer in your community This role is not eligible for relocation or immigration support. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin or disability. #J-18808-Ljbffr