Role:Associate - Transporters and hepatocytes research (DMPK)Department:DMPKLocation:HyderabadAbout Us:Sai Life Sciences is one of the fastest-growing Contract Research, Development, and Manufacturing Organizations (CRDMOs). As a pure-play, full-service partner, we collaborate with over 300 global innovator pharma and biotech companies to accelerate the discovery, development, and commercialization of their NCE programs. We have over 3000 employees across our facilities in India, the UK, and the USA, working together to deliver scientific excellence and customer success. We are a Great Place to Work certified organization with a culture of openness, mutual respect, and inclusivity. We embrace diversity and follow equal opportunity practices across all levels.Key Responsibilities : Hands-on experience in conducting transporter uptake and inhibition assays using HEK293 stably transfected cell lines. Prior experience in validation of transporter transfected cell lines and support the customers with customised assay conditions. Experience in conducting the oil spin method for assessing uptake and inhibition. Hands-on experience or ability to conduct CYP450 inhibition studies using hepatocytes. Experience in conducting in vitro transporter assays with radioisotope labelled compounds. Maintenance of cell line inventory and lab infrastructure. Support IND-enabling studies, routine screening, and generate high-quality data. Participation in scientific innovation projects in the field of drug transporters. Familiarity with the extended clearance classification system. Knowledge of data compilation and interpretation for test compound classification systems, either as substrates or uptake inhibitors. Ability to understand and read data, identify data variability, and participate in data review cycles with the QA team. Commitment to delivering data within agreed timelines ( Excellent communication and collaboration skills, working closely with team members. Good oral and written communication skills.Education and Experience: M Pharm (Pharmacology/Pharmaceutics) with 3-8 years of experience or MSc with 6-8+ years of experience in DMPK of small molecule drug discovery and development, preferably in a CRO or Biotech/Pharma industry. Knowledge of FDA and EMA industry guidance.
Job Title
Associate - Transporters and hepatocytes research ( DMPK)