Job Title

Role SummaryThe Senior Medical Director, Integrated Evidence Generation – Nephrology will serve as the strategic architect of Travere’s Medical Affairs–led evidence infrastructure. This role defines and executes a multi-year integrated evidence strategy spanning post-approval interventional and non-interventional studies, investigator-sponsored research (ISR), collaborative research, real-world evidence (RWE), and lifecycle management (LCM). The role chairs the Evidence Generation Committee and acts as the senior medical authority on post-approval and lifecycle evidence, partnering cross-functionally to strengthen Travere’s scientific credibility and long-term asset value.ResponsibilitiesDefine and lead a 3–5-year integrated evidence roadmap aligned to lifecycle and access priorities.Serve as Medical Affairs evidence leads for LCM planning and execution.Identify and address evidence gaps supporting label expansion, new subpopulations, combination strategies, durability, and long-term safety.Ensure evidence strategy strengthens regulatory positioning and lifecycle business cases.Partner with Clinical Development and Regulatory to align post-approval evidence with future development plans.Chair and govern the cross-functional Evidence Generation Committee.Establish clear prioritization criteria and portfolio governance processes.Oversee investment decisions across MA-led studies, ISR, collaborative research, and RWE.Ensure evidence investments are strategically aligned to lifecycle objectives.Provide executive-level updates to TA and GMA leadership.Establish and lead ISR governance framework within the TA.Define scientific prioritization aligned to strategic data gaps.Curate an ISR and collaborative research portfolio that advances guideline positioning, access strategy, and future development opportunities.Oversee partnerships with academic institutions, research networks, and Centers of Excellence.Monitor scientific impact and return on investment.Co-lead RWE strategy in partnership with Patient Access/HEOR.Align RWE initiatives with lifecycle, guideline, and access priorities.Identify and evaluate strategic data partnerships and registries.Ensure RWE outputs inform clinical practice insights, compendia engagement, and value demonstration.Establish and expand Travere’s Medical Affairs–led research capability.Develop scalable frameworks to support post-approval interventional, non-interventional, and implementation science studies.Identify opportunities where MA-led research complements Clinical Development and strengthens lifecycle strategy.Operationalize compliant, fit-for-purpose execution models appropriate for Travere.Represent Travere in strategic society research initiatives and academic collaborations.Engage key opinion leaders, steering committees, and research consortia.Serve as internal authority on evolving evidence methodologies and standards.Contribute to cross-functional planning, advisory boards, and broader Medical Affairs priorities based on expertise and organizational needs.Collaborate with field medical teams to execute external expert interactions, evidence-generation activities, and training programs aligned with emerging evidence and medical strategies.QualificationsAdvanced scientific degree (MD, PharmD, PhD).8+ years of experience in Medical Affairs, clinical research, evidence generation, or other relevant experience.Deep expertise in interventional and non-interventional study design, RWE methodologies, ISR governance, post-approval and lifecycle evidence strategy.Experience contributing to or leading lifecycle management planning.Demonstrated ability to influence executive decision-making.Proven ability to operate in a lean, high-accountability biotech environment.SkillsDemonstrated ability to influence important customers, challenge common perceptions, and implement medical affairs tools to improve patient care and outcomes.Exemplary verbal and written communication skills, including formal presentation skills, and well-developed interpersonal skills.Strong organizational skills with the ability to prioritize and execute against key objectives and deliverables, on time and within budget.Demonstrates the highest ethical standards with strong knowledge of and adherence to applicable regulatory, legal, and compliance requirements.Highly adaptable and resourceful, with the ability to prioritize, manage complexity, and collaborate effectively in a fast-paced, cross-functional environment.Additional RequirementsTravel up to 40% (ASN, ERA-EDTA, NKF, KOL symposiums, etc.) and may require some evenings and weekend availability.On-site work in San Diego; no role is 100% remote. #J-18808-Ljbffr