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6 days ago Be among the first 25 applicantsExperience, qualification, and soft skills, have you got everything required to succeed in this opportunity Find out below.Get AI-powered advice on this job and more exclusive features.We're seeking a Co-Founder with deep PROTAC/targeted protein degradation expertise to lead our medicinal chemistry platform and integrate protein degradation into our established multi-omic AI infrastructure. This is a ground-floor opportunity to build the first truly integrated precision protein degradation company.Our Differentiation: AI-driven target identification across the human proteome using multi-omic integration pipelines for PROTAC development enabling precision medicine approach to protein degradation and biomarker-guided patient stratification from day one.About Omnia TxOmnia Tx is pioneering precision-guided protein degradation through our proprietary multi-omic AI platform. We integrate proteomics, transcriptomics, metabolomics, genomics, and protein degradation chemistry to tackle cancer's most challenging targets.Our Mission: Transform undruggable proteins into precisely targeted therapies by seamlessly integrating proteomics, transcriptomics, metabolomics, genomics, and protein degradation chemistry through AI-driven biomarker discovery and patient stratification models.Current Founder: Alumni of CRUK Cancer Tech Accelerator 2021, Crick Institute BIA Pulse 2021 and former finalist in Astellas Future Innovator Prize as a founder of Omnia Biosystems among other highly selective venture building accelerators.What You'll DoStrategic Leadership Co-define company vision integrating computational insight with PROTAC development Lead medicinal chemistry platform development on a multi-omic infrastructure foundation Optimise pharmacokinetics and pharmacodynamics of PROTACs Represent company scientific vision to investors, partners, and scientific communityProgram Development Lead PROTAC discovery campaigns for AI-identified novel targets Execute structure-based drug design for transcription factors and kinases Build academic and industry collaborations for specialised chemistry expertise Create IP strategy around integrated AI-guided PROTAC developmentTeam Building & Culture Recruit medicinal chemistry team aligned with platform approach Establish scientific advisory board spanning AI, multi-omics, and protein degradation Foster collaborative culture bridging computational and experimental sciences Drive scientific excellence across interdisciplinary platformWhat You Bring PhD in Medicinal Chemistry, Chemical Biology, or related field 5+ years direct PROTAC development experience (industry or advanced academic) Expert knowledge of ubiquitinproteasome system (UPS) and protein degradation mechanisms Experience in modular PROTAC assembly including linker design and E3 ligase selection Track record of advancing molecules from hit to lead to candidate Strong understanding of structure-based drug design and ternary complex formation Experience integrating computational approaches with experimental chemistry Knowledge of biomarker development and precision medicinePreferred Qualifications Structure-based optimisation of PROTACs utilising computational methods like AlphaFold Target protein structure prediction and binding site identification Linker design and optimisation for ternary complex formation Structure-guided optimisation of target and E3 ligase binding domains Analysis of predicted ternary complex for improved PROTAC performance Background in multi-omic data integration or systems biology Industry experience in biotech/pharma with platform-based discovery Track record of team leadership in interdisciplinary environmentsWhy Join Omnia Tx?Revolutionary Platform First-of-its-kind integration of AI-driven multi-omics with protein degradation Competitive moat through proprietary biomarker-guided development approach Target-rich environment with AI continuously identifying new opportunities Precision medicine leadership in emerging protein degradation fieldTechnical Advantages AI/ML capabilities for target identification and patient stratification Platform development leveraging 4+ years of prior insights and learnings Clear pathway to biomarker-guided clinical developmentGrowth Potential Ground-floor role in category-defining precision medicine company Opportunity to lead integration of two transformative technologies (AI + protein degradation) Multiple high-value programs emerging from platform capabilities Clear path to strategic partnerships and clinical developmentCompensation & Equity Significant co-founder equity stake (negotiable based on experience) Equity-only position pending seed raise with substantial upside potential Performance-based equity incentives tied to platform and program milestones Professional development support for conferences and interdisciplinary trainingCurrent Stage & FundingStage: Pre-seed to seed (actively fundraising 2-3M)Timeline: Immediate start with co-founder equity negotiationLocation: Remote-first (initially)Recent Platform Development: Multi-omic data integration workflows operational on AWS infrastructure AI/ML frameworks established for target identification and patient stratification Academic partnerships in development for PROTAC chemistry expertise IP landscape analysis completed with provisional patent strategy developedApplication ProcessTo Apply: Please submit CV with details of your PROTAC development experience.Next Steps: Selected candidates will be contacted for an initial discussion.Omnia Tx welcomes applications from all backgrounds.Join us in building the first truly integrated precision protein degradation platform. If you're passionate about transforming how we discover, develop, and deploy targeted therapies through AI-driven multi-omic insights, we want to hear from you.Seniority levelSeniority levelExecutiveEmployment typeEmployment typePart-timeJob functionJob functionBusiness Development and SalesReferrals increase your chances of interviewing at Omnia Therapeutics by 2xGet notified about new Co-Founder jobs in London Area, United Kingdom.London, England, United Kingdom 1 week agoLondon, England, United Kingdom 4 months agoGlobal Internship Program at Nova FoundersLondon, England, United Kingdom 7 months agoLondon, England, United Kingdom 18 hours agoManagement Graduate Program at Nova FoundersLondon, England, United Kingdom 7 months agoFounder & CEO - AI Finance Companion for the Emergent AffluentsLondon, England, United Kingdom 5 days agoManagement Graduate Program at Nova FoundersLondon, England, United Kingdom 7 months agoExecutive Assistant to Founder/Chief Executive OfficerGreater London, England, United Kingdom 8 hours agoLondon, England, United Kingdom 35,000.00-45,000.00 1 month agoLondon, England, United Kingdom 2 weeks agoLondon, England, United Kingdom $70,000.00-$100,000.00 4 weeks agoLondon, England, United Kingdom 1 week agoLondon, England, United Kingdom 3 months agoE-Commerce Co-Founder / CCO (100 % remote) (m/f/d)London, England, United Kingdom 4 days agoFounder Associate at Private Equity InsightsLondon, England, United Kingdom 3 months agoEntrepreneur in Residence Internship at CFO InsightsLondon, England, United Kingdom 7 months agoLondon, England, United Kingdom 3 months agoLondon, England, United Kingdom 1 week agoLondon, England, United Kingdom 2 weeks agoLondon, England, United Kingdom 1 week agoLondon, England, United Kingdom 3 months agoLondon, England, United Kingdom 3 months agoLondon, England, United Kingdom 3 months agoLondon, England, United Kingdom 3 months agoWere unlocking community knowledge in a new way. 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