Job Title

Please ensure you read the below overview and requirements for this employment opportunity completely. Senior Scientist Bioinformatician (Data Analysis) (fulltime, permanent) South Mimms, Hertfordshire About the Agency Medicines and Healthcare products Regulatory Agency (MHRA) regulates medicines and medical devices in the UK. The Science and Research group delivers worldleading research and innovation, spanning six subgroups including Research and Development, where this role will be based. Role Overview Deliver advanced bioinformatics expertise to regulatory science research projects. Design, build and run reproducible NGS data analysis pipelines for genomics, transcriptomics, metagenomics, microbiome profiling and singlecell analysis. Support regulatory science, standards development and control testing. Key Responsibilities Lead the design, development and delivery of scalable bioinformatics pipelines (e.g. Nextflow, Python, R) for largescale NGS datasets. Manage cloudbased bioinformatics infrastructure (e.g. Google Cloud Platform) ensuring scalability, reproducibility, data governance and compliance with MHRA quality systems (ISO). Perform quality control, statistical analysis and biological interpretation of diverse NGS modalities, collaborating with SR&I and wider MHRA teams. Mentor junior bioinformaticians and laboratory scientists, contribute to publications and grant proposals, and integrate emerging technologies into core facility operations. Candidate Profile Extensive experience delivering largescale bioinformatics analysis using cloud computing environments. Proficiency in Bash, Python, R and workflow languages such as Nextflow. Experience with Linux, GitHub, Docker, Singularity and version control. Strong projectmanagement skills, documentation and communication of bioinformatics results. Proven ability to lead analytical components of complex, multistakeholder projects. Technical and Educational Requirements MSc (or equivalent) in Bioinformatics, Computational Biology or related discipline. Deep understanding of NGS data formats, bioinformatics tools and QC processes. Proficiency with version control, collaborative coding platforms, containerisation and cloud computing. Ability to interpret and communicate complex genomic data to diverse audiences. Behavioural and Experience Criteria Managing a Quality Service (Application, Interview) Making Effective Decisions (Application, Interview) Developing Self and Others (Application, Interview) Proven experience in highimpact bioinformatics analyses across NGS applications (Application, Interview, Presentation) Proficiency in developing and managing Nextflow workflows and scripting in Python, R or Perl (Application, Interview, Presentation, Test) Extensive experience with cloud computing and Unix/Linux environments (Application, Interview, Presentation, Test) Selection Process Online application questions based on Behaviour, Experience and Technical Success Profiles. Test details provided upon progression. Presentation to be prepared as part of the interview. Interview questions on Behaviour, Experience, Technical and Strengths Success Profiles. Other Considerations Competitors must meet UK immigration requirements and Civil Service nationality rules. Successful candidates must pass disclosure and barring checks, animalrights checks and may be subject to an internal fraud database check. COVID19 flexible hybrid working minimum 8 days onsite per month, up to 12 days depending on role; remote work possible at senior management discretion. Certain roles may require vaccinations and health surveillance. Eligibility and Contact Closing date: 9February. Shortlisting from 16February. xjdpvnf Interviews from 2March. For assistance or questions, contact