Job Title

Job Description Dept. Dermatology Title: Post Doc Fellow Physical work location: 787 11 th Avenue, 6 th Floor, New York, NY 10019 Name PI or Supervisor: Dr. Hongzhen Hu E: () Web link to Lab: Web link to Depu2019t : Administrative Contact: Pam Gassner/E: Qualifications Educational and other Requirements for the position: MD and/or PhD degree, and applicable experience and education Experience Required: 3+ years of relevant experience in laboratory. Specific skillsets required: basic flow cytometry, preparation of RNA, quantitative real-time PCR, RNA-seq, in vivo mouse work, basic staining and prep for imaging. Desired skillsets: single-cell bioinformatics experience, epigenomics background, calcium imaging. Goals/Outcomes of the Research Project: Knowledge of the underlying mechanisms of migraine and headache will lead to new rational-based treatment approaches by electively targeting specific pain signaling pathways in the trigeminal system. Responsibilities Details of Research Project: The Post Doc Fellow will work on pilot studies investigating how CGRP-expressing trigeminal sensory neurons communicate with immune cells in the meninges. They will use genetic models to stimulate or inhibit the CGRP-expressing trigeminal sensory neurons to perform gain and loss of function studies. They will also use reporter mice to trace nerve fibers of these neurons in young and aged mice to see if aging impacts the structure and function of these neurons and its impact on neuroimmune crosstalk in the meninges. Technical Duties: + Designing and executing scientific experiments + Regular presentation of data in lab meetings, work-in-progress, seminars, and national/international meetings + Provides data for grant submissions and progress reports for NIH and foundations + Attending meetings or taking part in conference calls with other clinicians and scientists + Analyzes and interprets research results and the scientific literature in connection with writing or editing high-quality grant fellowship applications, manuscripts, etc. + Helps other researchers translate data results into a manuscript format and propel them to publication + Effectively manages time, multi-task, and handle a high volume of work in a fast-paced environment. + Develops detailed project timelines according to team and project-specified deadlines. + Supervises technicians, graduate students, and junior postdoctoral fellows + Other relevant duties as needed About Us Strength through Unity and Inclusion The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinaiu2019s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual. At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history. About the Mount Sinai Health System: Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time u2014 discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patientsu2019 medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high