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Job Description Department: Stem Cell Biology & Regenerative Medicine Physical work location: (must be proper street address) 619 West 54 Street, 8 th floor Name PI or Supervisor: (include phone and email) Joel Blanchard and Web link to Lab: Web link to Department: Administrative Contact: (phone and email) Nyomi Cepeda and Qualifications Educational and other Requirements for the position: PhD Experience Required: 4-5 years Goals/Outcomes of the Research Project: Compensation Statement The Mount Sinai Health System (MSHS) provides salary ranges that comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $74, 692.00 - $80,000.00 Annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits. SPOC-UAW Local 4100 at Icahn School of Medicine (Post Docs), 865 - Cell Developmental & Regenerative Biology - ISM, Icahn School of Medicine Responsibilities Details of Research Project: The Blanchard Laboratory is seeking highly skilled, creative, and motivated scientists to join our team studying how genetic and environmental factors shape the human brainu2019s vulnerability to neurodegenerative disease. Our research focuses on uncovering the cellular and molecular mechanisms underlying Alzheimeru2019s disease and related neurodegenerative disorders, with the goal of identifying new therapeutic strategies. To accomplish this, the lab develops and applies advanced human iPSC-based brain models, including multicellular organoid and assembloid systems that recapitulate key aspects of human brain biology. These platforms are integrated with genomic, computational, and systems-level approaches to understand how genetic risk factors and environmental exposures drive disease processes. Technical Duties: (include any protocols) Projects in the laboratory span multiple areas of neurodegeneration research, including: Genetic risk mechanisms in Alzheimeru2019s disease (e.g., APOE biology) Neurovascular and glial contributions to neurodegeneration Lipid metabolism and metabolic stress in the aging brain Human brain organoid and assembloid engineering Multi-omics analysis of human brain tissue and disease models Our experimental platforms combine human iPSC models, post-mortem human brain analysis, and mouse models, enabling mechanistic discoveries that directly inform translational research. About Us Strength through Unity and Inclusion The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinaiu2019s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual. At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history. About the Mount Sinai Health System: Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time u2014 discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patientsu2019 medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high