Job Title

Our Protein Sciences group is looking for an Associate Scientist or Scientist I (lab-based role) with a background in protein chemistry to play an essential role in the purification and characterization of antibodies and recombinant proteins for research and development purposes. You will utilize your expertise in protein purification techniques to purify antibodies and other proteins of interest, ensuring high yield and purity. You will also analyze and characterize the purified proteins to ensure they meet project specifications. You will have the opportunity to present your data in internal and external meetings.Responsibilities:Perform protein purification using AKTA systems and various chromatographic techniques (affinity, ion exchange, size exclusion chromatography, etc.)Develop and implement efficient and scalable protein purification strategies for diverse proteins (including different antibody isotypes and recombinant proteins)Analyze the purity of purified proteins using techniques such as SDS or native PAGE, CE, SEC-HPLC, MALSMaintain lab equipment and prepare reagents and buffersTroubleshoot purification processes, develop and optimize protocols to improve yield and purityCollaborate with colleagues across the organization to ensure successful project completionFollow safe laboratory practices and maintain accurate and detailed laboratory notebookselectronic recordsSOPs (experience with Benchling is a plus)Stay current with the latest advancements in protein purification techniquesMay provide training and guidance to junior staff membersQualifications:Level commensurate with experience.Degree in Biochemistry, Protein Chemistry, Chemistry, or a related fieldBS + 11 years or MS + 6 years (Associate Scientist) in protein purification or Ph.D. with up to 2+ years experience (Scientist I)Strong working knowledge of various protein purification techniquesExperience with AKTA Pure or AVANT is a plusExperience with antibody analytics and one or more of the following techniques: ELISA, HPLC, SEC-MALS, SLSDLS is preferredExperience with automation and high throughput purification using Hamilton, Tecan, or equivalent technology is a plus.Excellent problem-solving and troubleshooting skills is a mustStrong organizational skills and the ability to manage multiple tasks simultaneouslystrong communication skills and attention to detailA good and respected team player.About IGM Biosciences, Inc.IGM Biosciences (Nasdaq: IGMS) is a clinical-stage biotechnology company committed to developing and delivering a new class of medicines to treat patients with cancer and autoimmune and inflammatory diseases. The Company's pipeline of clinical and preclinical assets is based on the IgM antibody, which has 10 binding sites, compared to conventional IgG antibodies with only 2 binding sites. We have created unique IgM antibodies with high selectivity, affinity, and avidity that may redefine what is possible for therapeutic antibody medicines. We believe our proprietary IgM antibody technology platform is particularly well suited for developing T cell engagers and receptor cross-linking agonists. The Company also has an exclusive worldwide collaboration agreement with Sanofi to create, develop, manufacture, and commercialize IgM antibody agonists against oncology, immunology, and inflammation targets. For more information, please visit Antibodies and Autoimmune and Inflammatory DiseasesAntibody treatments have revolutionized outcomes for patients with autoimmune and inflammatory diseases. We are committed to exploring how our IgM antibody platform's unique structure and binding properties can improve outcomes for patients with these serious conditions.IgM Antibodies and OncologyWe are applying the power of avidity and our IgM antibodies' strong and durable binding to create new treatment options for cancer patients. Our initial efforts in oncology are focused on the broad application of IgM antibodies to activate receptors to induce programmed death of cancer cells.